According to GlobalData’s company profile on ClearPoint Neuro, Transcranial ultrasound was a key innovation area identified from patents. ClearPoint Neuro‘s grant share as of January 2024 was 46%. Grant share is based on the ratio of number of grants to total number of patents.

Mri-guided system for precise placement of therapy devices

Source: United States Patent and Trademark Office (USPTO). Credit: ClearPoint Neuro Inc

A recently granted patent (Publication Number: US11872086B2) discloses a Magnetic Resonance Imaging (MRI)-guided method that involves providing a mount assembly with a base affixed to a patient’s skull, supporting a mount for holding an MRI visible elongate member. The method includes automatically determining a scan plane in 3D MRI space, identifying intrabody trajectories, comparing them to desired trajectories, calculating positional adjustments using positional adjustment members, and directing a piezoelectric drive system to adjust the mount’s position to achieve the desired trajectory. The system allows for precise positioning of medical devices for interventions in the brain, such as delivering therapeutic drugs or placing stimulation leads, with the drive system being non-ferromagnetic to ensure compatibility with MRI scanners.

Furthermore, the patent details additional features such as generating virtual intrabody trajectory lines, obtaining MRI image data, and utilizing high-intensity filtering to identify the location of the MRI visible elongate member. The method enables quick and accurate adjustments to achieve the desired intrabody trajectory, with the drive system comprising flexible drive cables attached to positional adjustment members. The system’s design allows for efficient and safe placement of interventional devices at target intrabody sites, showcasing advancements in MRI-guided procedures for neurosurgical interventions. The method’s ability to calculate adjustments and move the mount within minutes highlights its potential for enhancing precision and efficacy in medical procedures involving MRI guidance.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.


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