MetaMedical™ Solutions Inc

Asynchronous Neural Responses for Pain Treatment

According to GlobalData’s company profile on Nevro, Neuromodulation implants was a key innovation area identified from patents. Nevro‘s grant share as of January 2024 was 62%. Grant share is based on the ratio of number of grants to total number of patents.

Treatment of pain using asynchronous neural responses

Source: United States Patent and Trademark Office (USPTO). Credit: Nevro Corp

A recently granted patent (Publication Number: US11883670B2) outlines a method for treating pain in patients by directing an electrical signal to the spinal cord region through an implanted signal delivery element. The method involves adjusting the parameter values of the electrical signal based on the neural response evoked, aiming to induce a smoother and more pleasant sensation in the patient. This adjustment process is iteratively repeated until the desired sensation is achieved. The patent emphasizes the correlation between the pleasant sensation and an asynchronous neural response in the patient, with a reduction in the compound action potential amplitude indicating the effectiveness of the treatment.

Furthermore, the patent describes a spinal cord stimulation treatment system that includes a pulse generator and an implantable signal delivery element. The system is designed to automatically adjust the parameter values of the electrical signal based on the neural response received via a sensor implanted near the patient’s spinal cord. By iteratively repeating this process, the system aims to induce a smoother and more pleasant sensation in the patient. The patent highlights the importance of increasing the frequency of the electrical signal to achieve the desired outcome, with the system being capable of adjusting the frequency by preset increments until the optimal sensation is achieved. Overall, the patent presents a comprehensive approach to pain management through spinal cord stimulation, focusing on individualized parameter adjustments to enhance patient comfort and well-being.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.


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